Can You Develop a CBD Tolerance?

Can you build a tolerance to CBD Oil?

There is a lingering question surrounding CBD oil as to whether CBD tolerance builds up over time.

Can tolerance be developed with regular use?

Let’s find out…

Can You Build a Tolerance to CBD Oil?

You cannot build up a tolerance to CBD oil. The opposite is much more likely to be true.
You can build up a reverse tolerance to CBD, which means you need less over time to get the desired effect.

CBD Tolerance As CBD is a cannabinoid the same as THC, it would be natural to assume it has many of the same tendencies, including building a tolerance.

The truth is that CBD and THC share a few traits (they both affect the endocannabinoid system, for example), but they are, in fact, very different in other ways.

There are significant differences between CBD and THC.

CBD has become very popular for treating anxiety, which THC is known to trigger.

CBD also doesn’t trigger psychoactivity, which THC infamously does.

Another significant difference between the two is the risk of tolerance.

The main issue with THC is that there is a slow increase in tolerance levels when used for medicinal or recreational purposes.

The initial dose will eventually become ineffective when taken regularly.

CBD oil consumption does not create tolerance. On the contrary, oddly enough, it seems to have the opposite effect.

A much less well-known phenomenon is called reverse tolerance.

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How Does Tolerance Develop in the First Place?

Tolerance develops most commonly with drugs that bind directly to our endocannabinoid receptors (THC being an example).

Long-term use leads to an internal response from the endocannabinoid system, and our bodies adapt to the continual presence of the compound.

As such, a higher dosage is required to achieve the same effect.

Research has shown that long-term THC use leads to increased tolerance.

THC binds strongly to the cannabinoid receptor CB1, responsible for the psychoactive effect.

Over time, THC reduces the number of available cannabinoid receptors.

This was supported by a study conducted in 2012, which showed that chronic THC users had fewer cannabinoid receptors than non-users.

After a break from THC, the same users returned to lower dosages, and their cannabinoid receptor levels returned to normal.

NOTE – You might also enjoy reading this post about CBD withdrawal symptoms.

How Does CBD Reverse Tolerance?

As the name suggests, CBD reverse tolerance is the opposite of tolerance to CBD.

Continued substance use reduces tolerance, and the user needs less substance to achieve the desired effect.

Most substances cause people to experience increased tolerance levels – everything from pharmaceuticals, nicotine, alcohol, and hard drugs like cocaine and methamphetamine.

In some rare cases with alcohol, the opposite is experienced due to severe liver damage.

There are limited studies on the tolerance of CBD, but the consensus is that there is little to no risk of developing a tolerance.

This is because CBD does not technically bind to any single cannabinoid receptor, eliminating the tolerance problem.

CBD promotes increased receptor activity, unlike THC, which reduces cannabinoid receptors over time.

Other receptors, such as GABA and NMDA receptors, also respond to CBD and have been shown to play a part in reverse tolerance.

Whatever the reason for CBD oil reverse tolerance, consumers will find that they can slowly decrease their dosage over time.

(You may also find this article looking at the pros and cons of CBD oil useful to read).

Personal Anecdotes About CBD Oil Tolerance

Some personal reports are online where people claim to have experienced CBD tolerance when taking it for anxiety.

However, on closer inspection, some of these complaints were down to users struggling to find a high-quality source of CBD oil.

There is, however, something to be aware of called CBD saturation. This is often found in users taking CBD oil for epilepsy.

After long-term CBD use, the users may begin to experience seizures again.

Common sense would dictate at that point that a higher dosage may be needed, but there is evidence to suggest that the opposite may be the answer, and a lower dose or simply a break from CBD oil could help restore its effectiveness.

The truth is that more research needs to be conducted about tolerance to CBD oil. However, in the meantime, users have been able to find their solutions with excellent results.

Related PostCBD Side Effects.

Final Notes On if You Can Build a Tolerance to CBD Oil

Building a tolerance to CBD oil is impossible due to how it interacts with the body.

The opposite is true; over time, a reverse tolerance may occur with regular consumption where less CBD is needed to garner the same effects.

So, to conclude, CBD tolerance is nothing to worry about.

Especially if you use high-quality CBD oil, you are unlikely to experience any tolerance to CBD.

That is the end of this post looking at the question – can you build a tolerance to CBD oil?

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